Cochrane at crossroads over drug company sponsorship

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Influence of drug company authorship and sponsorship on drug trial outcomes.

Studies of drug treatments are more likely to report favourable outcomes when they are funded by the pharmaceutical industry. We compared drug trials reported in three major psychiatric journals to investigate these influences. Independent studies were more likely to report negative findings than industry-funded studies. However, the involvement of a drug company employee had a much greater eff...

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Many studies have shown that pharmaceutical companies' funding of clinical trials is associated with pro-industry results. This article reviews the literature on that association, confirming its existence, and discusses its causes and potential responses. The mechanisms of industry influence are varied, more than is usually acknowledged. It is straightforward to identify a number of distinct ki...

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Cochrane in CORR ®: Industry Sponsorship and Research Outcome.

I n the past decade, the number of clinical trials funded by industry has substantially increased in the United States [9]. The drug and device industry now funds six times more clinical trials than the federal government [3]. This may be cause for concern, as publication agreements in which industry sponsors constrain academic authors’ independence are common [5] and several research articles ...

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ژورنال

عنوان ژورنال: BMJ

سال: 2003

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.327.7420.924